Ketamine for Post-Operative Analgesia in Paediatrics

Novel concepts of analgesia for post operative pain: Multimodal analgesia

Quality of post-operative analgesia after epidural dexmedetomidine and ketamine: A comparative pilot study

Hip fractures are intensely painful, so post‐operative analgesia is an integral part of patient care for early rehabilitation and mobility.[1] Local anaesthetics with epidural additives ideally should provide stable haemodynamics and prolonged analgesia. There is limited literature comparing dexmedetomidine and ketamine as epidural additives. We conducted a study of continuous epidural infusion...

Post-operative analgesia after remifentanil-based anaesthesia

Remifentanil is a very potent ultrashort acting opioid, that is mainly used as a part of balanced anaesthesia regimens for management of intraoperative pain. Effective plasma levels of this drug can only be maintained using continuous infusions, as tissue esterases inactivate remifentanil within minutes following its application. The advantages of this specific pharmacokinetic behaviour are tha...

Post-operative Analgesia in Opioid Dependent Patients: Comparison of ‎Intravenous Morphine and Sublingual Buprenorphine

Background: Acute and chronic pain is prevalent in patients with opioid dependence. Lack of knowledge concerning the complex relationship between pain, opioid use, and withdrawal syndrome can account for the barriers encountered for pain management. This study was designed to evaluate the efficacy of sublingual (SL) buprenorphine for post-operative analgesia, compared with intravenous (IV) morp...

Epidural ketamine for postoperative analgesia.

·T WO factors have increased interest in ketamine for postoperative analgesia. The first was the discovery of the N-Methyl-D-aspartate (NMDA) receptor and its role in central pain processing and spinal cord neural plasticity.1 Ketamine is one of two clinically useful NMDA receptor antagonists available (the other is dextromethorphan). Ketarnine binds non-competitively to the PCI, (phencyclidine...